Geeez! Eventually I have submitted the thesis and given the defense presentation! My PhD project is about representing the results coming from microarray data analysis. I represent concepts like: sets of differentially expressed genes, results from clustering algorithms, claims about the role of genes in a biological pathway. I use Semantic Web technologies and an OWL model (ontology) to provide a formal representation of such knowledge. All is focused on assertions (e.g.: “IL2 is expressed under LPS infection condition”), which may be supported by experimental evidence (e.g.: a data set) or other kinds of evaluations, including ranking and comments from the users. Moreover, users and their roles (e.g.: is an expert on Immunology) may be considedered, especially for ranking the assertions. I have also developed a demo, based on the Makna Semantic Wiki.
Written by Marco Brandizi
I'm the owner of this personal site. I'm a geek, I'm specialised in hacking software to deal with heaps of data, especially life science data. I'm interested in data standards, open culture (open source, open data, anything about openness and knowledge sharing), IT and society, and more. Further info here.